|
Immunopharmacology is the intersection of immunology and pharmacology. This specialty course focuses on the mechanism of action of pharmacologic agents that regulate immune response and the physiologic, pathologic, and pharmacological role of the products of immune response. A notable feature of immunopharmacology, compared to classic pharmacology, is the object of study that include a large class of immune regulation drugs focusing on adjusting the body's natural resistance to disease, treatment of cancer and infectious diseases and autoimmune diseases. These therapeutic agents have a greater potential for development compared to traditional medicine. The first chapter in this course is aimed for students who have not previously taken a course in Basic Immunology. Chapters 2 and 3 introduce the concept of cytokines, their receptors and signaling pathways. The subsequent chapters focus on immune-related diseases and immune-drug treatment. The last part of the course includes chapters on immune drug development and advanced topics in immunopharmacology. This course provides most basic principles of immunopharmacology by equally emphasizing the disciplines of immunology and pharmacology, which will be valuable for both the professional as well as graduate students.
Chapter 1: Overview of Immunopharmacology
Focus on the origin and research progress of Immunopharmacology, and the basic technology in Immunopharmacology study
Chapter 2: Role of Cytokines
Focus on interleukin family, tumor necrosis factor and chemokines
Chapter 3: Cytokine receptors and Signaling
Focus on chemokine receptors and the downstream signal transduction
Chapter 4: Immunosuppressive Agents
Focus on autoimmune diseases and immunosuppressive agents
Chapter 5: Acquired Immune Deficiency Syndrome and Therapeutic Agents
Focus on agents for allergic disease, AIDS, tissue transplantation and cancer immunotherapy
Chapter 6: Monoclonal Antibodies as Therapeutic Agents
Focus on production of monoclonal antibodies and application
Chapter 7: Gene Therapy
Focus on vector for gene therapy and treatment of disease by gene therapy
Chapter 8: High-throughput screening for immune drug and new drug discovery
Focus on the concepts, contents, screening strategy and feature for immune drug discovery
|
